Endocrine Abstracts

Background: Hyperhomocysteinemia is an independent risk factor foratherosclerosis (1,2). Elevated plasma total homocysteine(t-Hcy) levels havebeen described in primary hypothyroidism (3,4). Subclinical hypothyroidismhas also been found to be associated with atherosclerosis (5).Hypothyroidism decreases hepatic levels of enzymes involved in theremethylation pathway of homocysteine and renal excretion of t-Hcy (6,7).The present study evaluates t-Hcy in sub...